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Microbiology with Diseases by Body System 5th Edition by Robert Bauman, ISBN-13: 978-0134618449

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Description

Description

Microbiology with Diseases by Body System 5th Edition by Robert Bauman, ISBN-13: 978-0134618449

[PDF eBook eTextbook]

  • Publisher: ‎ Pearson; 5th edition (January 6, 2017)
  • Language: ‎ English
  • 944 pages (Large Size: 63 MB)

  • ISBN-10: ‎ 0134618440
  • ISBN-13: ‎ 978-0134618449

Due to its large file size, this book may take longer to download.

For pre-nursing and allied health students (including mixed-majors courses).

Invest in your future: microbiology matters.

Dr. Robert Bauman’s Microbiology with Diseases by Body System, 5th Edition helps students visualize the invisible and practice critical thinking with real-world problems and clinical applications. The textbook includes QR codes for Dr. Bauman Video Tutors and Disease in Depth features that foster understanding and encourage students to explore microbiology. The continued focus on clinical situations prepares students for future opportunities in applied practice and healthcare careers. With the 5th Edition, new Solve the Problem features ask students to work through real-world microbiology problems and offer instructors active-learning worksheets for their course. This edition results from a collaborative effort of educators, students, editors, and top scientific illustrators to deliver a textbook that presents the latest scientific and educational research and data in microbiology.

Table of Contents:

Micro Biology With Diseases by Body System

About the Author

Preface

New to This Edition

Chapter-by-Chapter Revisions

Reviewers for the Fifth Edition

Contents

Feature Boxes

1 A Brief History of Microbiology

The Early Years of Microbiology

What Does Life Really Look Like?

Learning Outcomes

How Can Microbes Be Classified?

Learning Outcomes

Bacteria and Archaea

Fungi

Protozoa

Algae

Other Organisms of Importance to Microbiologists

The Golden Age of Microbiology

Learning Outcomes

Does Microbial Life Spontaneously Generate?

Learning Outcomes

Redi’s Experiments

Needham’s Experiments

Spallanzani’s Experiments

Pasteur’s Experiments

The Scientific Method

What Causes Fermentation?

Learning Outcomes

Pasteur’s Experiments

Buchner’s Experiments

What Causes Disease?

Learning Outcomes

Koch’s Experiments

Koch’s Postulates

Gram’s Stain

How Can We Prevent Infection and Disease?

Learning Outcomes

Semmelweis and Hand Washing

Lister’s Antiseptic Technique

Nightingale and Nursing

Snow and Epidemiology

Jenner’s Vaccine

Ehrlich’s “Magic Bullets”

The Modern Age of Microbiology

Learning Outcome

What Are the Basic Chemical Reactions of Life?

How Do Genes Work?

Microbial Genetics

Molecular Biology

Recombinant DNA Technology

Gene Therapy

What Roles Do Microorganisms Play in the Environment?

Learning Outcome

How Do We Defend Against Disease?

What Will the Future Hold?

Chapter Summary

The Early Years of Microbiology

The Golden Age of Microbiology

The Modern Age of Microbiology

Questions for Review

Multiple Choice

Fill in the Blanks

Short Answer

Matching

Visualize It!

Critical Thinking

Concept Mapping

2 The Chemistry of Microbiology

Atoms

Learning Outcome

Atomic Structure

Learning Outcomes

Isotopes

Learning Outcome

Electron Configurations

Learning Outcome

Chemical Bonds

Learning Outcomes

Nonpolar Covalent Bonds

Learning Outcomes

Polar Covalent Bonds

Learning Outcome

Ionic Bonds

Learning Outcomes

Hydrogen Bonds

Learning Outcome

Chemical Reactions

Learning Outcome

Synthesis Reactions

Learning Outcomes

Decomposition Reactions

Learning Outcome

Exchange Reactions

Learning Outcome

Water, Acids, Bases, and Salts

Water

Learning Outcome

Acids and Bases

Learning Outcome

Salts

Organic Macromolecules

Functional Groups

Learning Outcome

Lipids

Learning Outcomes

Fats

Phospholipids

Waxes

Steroids

Carbohydrates

Learning Outcome

Monosaccharides

Disaccharides

Polysaccharides

Proteins

Learning Outcomes

Amino Acids

Peptide Bonds

Protein Structure

Nucleotides and Nucleic Acids

Learning Outcomes

Nucleotides and Nucleosides

Nucleic Acid Structure

Nucleic Acid Function

ATP (Adenosine Triphosphate)

Chapter Summary

Atoms

Chemical Bonds

Chemical Reactions

Water, Acids, Bases, and Salts

Organic Macromolecules

Questions for Review

Multiple Choice

Fill in the Blanks

Visualize It!

Short Answer

Critical Thinking

Concept Mapping

3 Cell Structure and Function

Processes of Life

Learning Outcome

Prokaryotic and Eukaryotic Cells: An Overview

Learning Outcome

External Structures of Bacterial Cells

Glycocalyces

Learning Outcomes

Flagella

Learning Outcomes

Structure

Arrangement

Function

Fimbriae and Pili

Learning Outcome

Bacterial Cell Walls

Learning Outcomes

Gram-Positive Bacterial Cell Walls

Learning Outcome

Gram-Negative Bacterial Cell Walls

Learning Outcome

Bacteria Without Cell Walls

Bacterial Cytoplasmic Membranes

Structure

Learning Outcomes

Function

Learning Outcomes

Passive Processes

Diffusion

Facilitated Diffusion

Osmosis

Active Processes

Active Transport

Group Translocation

Bacterial Secretion Systems

Cytoplasm of Bacteria

Learning Outcomes

Cytosol

Inclusions

Endospores

Nonmembranous Organelles

Learning Outcome

Ribosomes

Cytoskeleton

External Structures of Archaea

Glycocalyces

Learning Outcome

Flagella

Learning Outcomes

Fimbriae and Hami

Learning Outcomes

Archaeal Cell Walls and Cytoplasmic Membranes

Learning Outcomes

Cytoplasm of Archaea

Learning Outcome

External Structure of Eukaryotic Cells

Glycocalyces

Learning Outcome

Eukaryotic Cell Walls and Cytoplasmic Membranes

Learning Outcomes

Cytoplasm of Eukaryotes

Learning Outcomes

Flagella

Learning Outcome

Structure and Arrangement

Function

Cilia

Learning Outcomes

Other Nonmembranous Organelles

Learning Outcomes

Ribosomes

Cytoskeleton

Centrioles and Centrosome

Membranous Organelles

Learning Outcomes

Nucleus

Endoplasmic Reticulum

Golgi Body

Lysosomes, Peroxisomes, Vacuoles, and Vesicles

Mitochondria

Chloroplasts

Endosymbiotic Theory

Learning Outcomes

Chapter Summary

Processes of Life

Prokaryotic and Eukaryotic Cells: An Overview

External Structures of Bacterial Cells

Bacterial Cell Walls

Bacterial Cytoplasmic Membranes

Cytoplasm of Bacteria

External Structures of Archaea

Archaeal Cell Walls and Cytoplasmic Membranes

Cytoplasm of Archaea

External Structure of Eukaryotic Cells

Eukaryotic Cell Walls and Cytoplasmic Membranes

Cytoplasm of Eukaryotes

Questions for Review

Multiple Choice

Matching

Visualize It!

Short Answer

Critical Thinking

Concept Mapping

4 Microscopy, Staining, and Classification

Units of Measurement

Learning Outcomes

Microscopy

Learning Outcome

General Principles of Microscopy

Learning Outcomes

Wavelength of Radiation

Magnification

Resolution

Contrast

Light Microscopy

Learning Outcomes

Bright-Field Microscopes

Simple Microscopes

Compound Microscopes

Dark-Field Microscopes

Phase Microscopes

Phase-Contrast Microscopes

Differential Interference Contrast Microscopes

Fluorescence Microscopes

Confocal Microscopes

Electron Microscopy

Learning Outcome

Transmission Electron Microscopes

Scanning Electron Microscopes

Probe Microscopy

Learning Outcome

Scanning Tunneling Microscopes

Atomic Force Microscopes

Staining

Preparing Specimens for Staining

Learning Outcome

Principles of Staining

Learning Outcome

Simple Stains

Learning Outcome

Differential Stains

Gram Stain

Acid-Fast Stain

Endospore Stain

Histological Stains

Special Stains

Negative (Capsule) Stain

Flagellar Stain

Staining for Electron Microscopy

Learning Outcome

Classification and Identification of Microorganisms

Learning Outcome

Linnaeus and Taxonomic Categories

Learning Outcomes

Domains

Learning Outcome

Taxonomic and Identifying Characteristics

Learning Outcome

Physical Characteristics

Biochemical Tests

Serological Tests

Phage Typing

MALDI-TOF Mass Spectrometry

Analysis of Nucleic Acids

Taxonomic Keys

Chapter Summary

Units of Measurement

Microscopy

Staining

Classification and Identification of Microorganisms

Questions for Review

Multiple Choice

Fill in the Blanks

Short Answer

Visualize It!

Critical Thinking

Concept Mapping

5 Microbial Metabolism

Basic Chemical Reactions Underlying Metabolism

Catabolism and Anabolism

Learning Outcome

Oxidation and Reduction Reactions

Learning Outcome

ATP Production and Energy Storage

Learning Outcome

The Roles of Enzymes in Metabolism

Learning Outcomes

Naming and Classifying Enzymes

The Makeup of Enzymes

Enzyme Activity

Temperature

pH

Enzyme and Substrate Concentration

Control of Enzymatic Activity

Carbohydrate Catabolism

Learning Outcome

Glycolysis

Cellular Respiration

Learning Outcomes

Synthesis of Acetyl-CoA

The Citric Acid (Krebs) Cycle

Electron Transport

Chemiosmosis

Metabolic Diversity

Learning Outcomes

Fermentation

Learning Outcomes

Other Catabolic Pathways

Lipid Catabolism

Learning Outcome

Protein Catabolism

Learning Outcome

Photosynthesis

Learning Outcome

Chemicals and Structures

Learning Outcome

Light-Dependent Reactions

Learning Outcomes

Cyclic Photophosphorylation

Noncyclic Photophosphorylation

Light-Independent Reactions

Learning Outcomes

Other Anabolic Pathways

Learning Outcome

Carbohydrate Biosynthesis

Learning Outcome

Lipid Biosynthesis

Learning Outcome

Amino Acid Biosynthesis

Learning Outcome

Nucleotide Biosynthesis

Learning Outcome

Integration and Regulation of Metabolic Functions

Learning Outcomes

Chapter Summary

Basic Chemical Reactions Underlying Metabolism

Carbohydrate Catabolism

Other Catabolic Pathways

Photosynthesis

Other Anabolic Pathways

Integration and Regulation of Metabolic Functions

Questions for Review

Multiple Choice

Matching

Fill in the Blanks

Visualize It!

Short Answer

Critical Thinking

Concept Mapping

6 Microbial Nutrition and Growth

Growth Requirements

Nutrients: Chemical and Energy Requirements

Learning Outcomes

Sources of Carbon, Energy, and Electrons

Oxygen Requirements

Nitrogen Requirements

Other Chemical Requirements

Physical Requirements

Learning Outcome

Temperature

pH

Physical Effects of Water

Osmotic Pressure

Hydrostatic Pressure

Associations and Biofilms

Learning Outcome

Culturing Microorganisms

Clinical Sampling

Learning Outcome

Obtaining Pure Cultures

Learning Outcome

Streak Plates

Pour Plates

Other Isolation Techniques

Culture Media

Learning Outcomes

Defined Media

Complex Media

Selective Media

Enrichment Culture

Differential Media

Anaerobic Media

Transport Media

Special Culture Techniques

Learning Outcome

Animal and Cell Culture

Low-Oxygen Culture

Preserving Cultures

Learning Outcome

Growth of Microbial Populations

Learning Outcome

Generation Time

Learning Outcome

Mathematical Considerations in Population Growth

Learning Outcome

Phases of Microbial Population Growth

Learning Outcomes

Lag Phase

Log Phase

Stationary Phase

Death Phase

Continuous Culture in a Chemostat

Learning Outcome

Measuring Microbial Reproduction

Learning Outcome

Direct Methods Not Requiring Incubation

Microscopic Counts

Electronic Counters

Direct Methods Requiring Incubation

Serial Dilution and Viable Plate Counts

Membrane Filtration

Most Probable Number

Indirect Methods

Turbidity

Metabolic Activity

Dry Weight

Molecular Methods

Chapter Summary

Growth Requirements

Culturing Microorganisms

Growth of Microbial Populations

Questions for Review

Multiple Choice

Fill in the Blanks

Visualize It!

Short Answer

Critical Thinking

Concept Mapping

7 Microbial Genetics

The Structure and Replication of Genomes

Learning Outcome

The Structure of Nucleic Acids

Learning Outcome

The Structure of Prokaryotic Genomes

Learning Outcomes

Prokaryotic Chromosomes

Plasmids

The Structure of Eukaryotic Genomes

Learning Outcome

Nuclear Chromosomes

Extranuclear Chromosomes in Eukaryotes

DNA Replication

Learning Outcomes

Initial Processes in Bacterial DNA Replication

Continual Synthesis of the Leading Strand

Fragmented Synthesis of the Lagging Strand

Other Characteristics of Bacterial DNA Replication

Replication of Eukaryotic DNA

Gene Function

The Relationship Between Genotype and Phenotype

Learning Outcome

The Transfer of Genetic Information

Learning Outcome

The Events in Transcription

Learning Outcomes

Initiation of Transcription

Elongation of the RNA Transcript

Termination of Transcription

Self-Termination

Rho-Dependent Termination

Transcriptional Differences in Eukaryotes

Translation

Learning Outcomes

The Genetic Code

Participants in Translation

Messenger RNA

Transfer RNA

Ribosomes and Ribosomal RNA

Events in Translation

Elongation

Termination

Translational Differences in Eukaryotes

Regulation of Genetic Expression

Learning Outcomes

The Nature of Prokaryotic Operons

The Lactose Operon, an Inducible Operon

Positive Regulation by CAP

Repression and Induction

The Tryptophan Operon, a Repressible Operon

RNA Molecules Can Control Translation

Mutations of Genes

Learning Outcome

Types of Mutations

Learning Outcome

Effects of Point Mutations

Learning Outcome

Mutagens

Learning Outcomes

Radiation

Chemical Mutagens

Nucleotide Analogs

Nucleotide-Altering Chemicals

Frameshift Mutagens

Frequency of Mutation

Learning Outcome

DNA Repair

Learning Outcome

Direct Repair

Single-Strand Repair

Error-Prone Repair

Identifying Mutants, Mutagens, and Carcinogens

Learning Outcomes

Positive Selection

Negative (Indirect) Selection

The Ames Test for Identifying Mutagens

Genetic Recombination and Transfer

Learning Outcome

Horizontal Gene Transfer Among Prokaryotes

Learning Outcomes

Transformation

Transduction

Bacterial Conjugation

Transposons and Transposition

Learning Outcomes

Chapter Summary

The Structure and Replication of Genomes

Gene Function

Mutations of Genes

Genetic Recombination and Transfer

Questions for Review

Multiple Choice

Fill in the Blanks

Short Answer

Visualize It!

Critical Thinking

Concept Mapping

8 Recombinant DNA Technology

The Role of Recombinant DNA Technology in Biotechnology

Learning Outcomes

Tools of Recombinant DNA Technology

Synthetic Nucleic Acids

Learning Outcomes

The Polymerase Chain Reaction: Multiplying DNA In Vitro

Learning Outcome

Mutagens and Mutagenesis

Learning Outcomes

Reverse Transcriptase: To Synthesize cDNA

Learning Outcome

Restriction Enzymes

Learning Outcomes

Vectors

Learning Outcome

CRISPR

Learning Outcome

Techniques of Recombinant DNA Technology

Selecting a Clone of Recombinant Cells

Learning Outcome

Separating DNA Molecules: Gel Electrophoresis and the Southern Blot

Learning Outcome

DNA Microarrays

Learning Outcome

Inserting DNA into Cells

Learning Outcome

Applications of Recombinant DNA Technology

Genetic Mapping

Learning Outcomes

Locating Genes

Genomics and Nucleotide Sequencing

Functional Genomics

Microbial Community Studies

Pharmaceutical and Therapeutic Applications

Learning Outcomes

Protein Synthesis

Vaccine Production

Genetic Screening

Gene Therapy

Medical Diagnosis

Xenotransplantation

Biomedical Animal Models

Agricultural Applications

Learning Outcome

Herbicide Tolerance

Pest Resistance

Salt Tolerance

Freeze Resistance

Improvements in Nutritional Value and Yield

The Ethics and Safety of Recombinant DNA Technology

Learning Outcome

Chapter Summary

The Role of Recombinant DNA Technology in Biotechnology

Tools of Recombinant DNA Technology

Techniques of Recombinant DNA Technology

Applications of Recombinant DNA Technology

The Ethics and Safety of Recombinant DNA Technology

Questions for Review

Multiple Choice

Modified True/False

Short Answer

Visualize It!

Critical Thinking

Concept Mapping

9 Controlling Microbial Growth in the Environment

Basic Principles of Microbial Control

Terminology of Microbial Control

Learning Outcomes

Microbial Death Rates

Learning Outcome

Action of Antimicrobial Agents

Learning Outcome

Alteration of Cell Walls and Membranes

Damage to Proteins and Nucleic Acids

The Selection of Microbial Control Methods

Factors Affecting the Efficacy of Antimicrobial Methods

Learning Outcomes

Site to Be Treated

Relative Susceptibility of Microorganisms

Environmental Conditions

Biosafety Levels

Learning Outcome

Physical Methods of Microbial Control

Learning Outcome

Heat-Related Methods

Learning Outcomes

Moist Heat

Boiling

Autoclaving

Pasteurization

Ultra-High-Temperature Sterilization

Dry Heat

Refrigeration and Freezing

Learning Outcome

Desiccation and Lyophilization

Learning Outcome

Filtration

Learning Outcome

Osmotic Pressure

Learning Outcome

Radiation

Learning Outcome

Ionizing Radiation

Nonionizing Radiation

Chemical Methods of Microbial Control

Learning Outcome

Phenol and Phenolics

Learning Outcome

Alcohols

Learning Outcome

Halogens

Learning Outcome

Oxidizing Agents

Learning Outcome

Surfactants

Learning Outcome

Heavy Metals

Learning Outcome

Aldehydes

Learning Outcome

Gaseous Agents

Learning Outcome

Enzymes

Learning Outcome

Antimicrobial Drugs

Learning Outcome

Methods for Evaluating Disinfectants and Antiseptics

Learning Outcome

Phenol Coefficient

Use-Dilution Test

Kelsey-Sykes Capacity Test

In-Use Test

Development of Resistant Microbes

Chapter Summary

Basic Principles of Microbial Control

The Selection of Microbial Control Methods

Physical Methods of Microbial Control

Chemical Methods of Microbial Control

Questions for Review

Multiple Choice

Short Answer

Visualize It!

Critical Thinking

Concept Mapping

10 Controlling Microbial Growth in the Body: Antimicrobial Drugs

The History of Antimicrobial Agents

Learning Outcomes

Mechanisms of Antimicrobial Action

Learning Outcomes

Inhibition of Cell Wall Synthesis

Learning Outcome

Inhibition of Synthesis of Bacterial Walls

Inhibition of Synthesis of Fungal Walls

Inhibition of Protein Synthesis

Learning Outcomes

Interference with Prokaryotic Ribosomes

Interference with Charging of Transfer RNA Molecules

Disruption of Cytoplasmic Membranes

Learning Outcome

Inhibition of Metabolic Pathways

Learning Outcomes

Inhibition of Nucleic Acid Synthesis

Learning Outcome

Prevention of Virus Attachment, Entry, or Uncoating

Learning Outcome

Clinical Considerations in Prescribing Antimicrobial Drugs

Learning Outcome

Spectrum of Action

Learning Outcome

Effectiveness

Learning Outcome

Diffusion Susceptibility Test

Minimum Inhibitory Concentration (MIC) Test

Minimum Bactericidal Concentration (MBC) Test

Routes of Administration

Learning Outcome

Safety and Side Effects

Learning Outcomes

Toxicity

Allergies

Disruption of Normal Microbiota

Resistance to Antimicrobial Drugs

The Development of Resistance and Persister Cells

Learning Outcomes

Mechanisms of Resistance

Learning Outcomes

Multiple Resistance and Cross Resistance

Learning Outcome

Retarding Resistance

Learning Outcome

Chapter Summary

The History of Antimicrobial Agents

Mechanisms of Antimicrobial Action

Clinical Considerations in Prescribing Antimicrobial Drugs

Resistance to Antimicrobial Drugs

Questions for Review

Multiple Choice

Visualize It!

Short Answer

Critical Thinking

Concept Mapping

11 Characterizing and Classifying Prokaryotes

General Characteristics of Prokaryotic Organisms

Morphology of Prokaryotic Cells

Learning Outcome

Endospores

Learning Outcome

Reproduction of Prokaryotic Cells

Learning Outcomes

Arrangements of Prokaryotic Cells

Learning Outcome

Modern Prokaryotic Classification

Learning Outcomes

Survey of Archaea

Learning Outcome

Extremophiles

Learning Outcome

Thermophiles

Halophiles

Methanogens

Learning Outcome

Survey of Bacteria

Deeply Branching and Phototrophic Bacteria

Learning Outcomes

Deeply Branching Bacteria

Phototrophic Bacteria

Cyanobacteria

Green and Purple Phototrophic Bacteria

Low G + C Gram-Positive Bacteria

Learning Outcomes

Clostridia

Mycoplasmas

Other Low G + C Gram-Positive Bacilli and Cocci

Bacillus

Listeria

Lactobacillus

Streptococcus and Enterococcus

Staphylococcus

High G + C Gram-Positive Bacteria

Learning Outcomes

Corynebacterium

Mycobacterium

Actinomycetes

Actinomyces

Nocardia

Streptomyces

Gram-Negative Proteobacteria

Learning Outcome

Class Alphaproteobacteria

Learning Outcomes

Nitrogen Fixers

Nitrifying Bacteria

Purple Nonsulfur Phototrophs

Pathogenic Alphaproteobacteria

Other Alphaproteobacteria

Class Betaproteobacteria

Learning Outcome

Pathogenic Betaproteobacteria

Other Betaproteobacteria

Class Gammaproteobacteria

Learning Outcomes

Purple Sulfur Bacteria

Intracellular Pathogens

Methane Oxidizers

Glycolytic Facultative Anaerobes

Pseudomonads

Class Deltaproteobacteria

Learning Outcome

Class Epsilonproteobacteria

Learning Outcome

Class Zetaproteobacteria

Learning Outcome

Other Gram-Negative Bacteria

Learning Outcomes

Chlamydias

Spirochetes

Bacteroids

Chapter Summary

General Characteristics of Prokaryotic Organisms

Modern Prokaryotic Classification

Survey of Archaea

Survey of Bacteria

Questions for Review

Modified True/False

Multiple Choice

Matching

Short Answer

Visualize It!

Critical Thinking

Concept Mapping

12 Characterizing and Classifying Eukaryotes

General Characteristics of Eukaryotic Organisms

Reproduction of Eukaryotes

Learning Outcomes

Nuclear Division

Mitosis

Meiosis

Cytokinesis (Cytoplasmic Division)

Schizogony

Classification of Eukaryotic Organisms

Learning Outcomes

Protozoa

Learning Outcome

Distribution of Protozoa

Morphology of Protozoa

Nutrition of Protozoa

Reproduction of Protozoa

Classification of Protozoa

Learning Outcomes

Parabasala

Diplomonadida

Euglenozoa

Euglenids

Kinetoplastids

Alveolates

Ciliates

Apicomplexans

Dinoflagellates

Rhizaria

Amoebozoa

Fungi

Learning Outcome

The Significance of Fungi

Learning Outcome

Morphology of Fungi

Learning Outcome

Nutrition of Fungi

Learning Outcome

Reproduction of Fungi

Learning Outcomes

Budding and Asexual Spore Formation

Sexual Spore Formation

Classification of Fungi

Learning Outcomes

Division Zygomycota

Microsporidia

Division Ascomycota

Division Basidiomycota

Deuteromycetes

Lichens

Learning Outcomes

Algae

Learning Outcome

Distribution of Algae

Morphology of Algae

Reproduction of Algae

Learning Outcome

Classification of Algae

Learning Outcomes

Division Chlorophyta (Green Algae)

Kingdom Rhodophyta (Red Algae)

Phaeophyta (Brown Algae)

Chrysophyta (Golden Algae, Yellow-Green Algae, and Diatoms)

Water Molds

Learning Outcome

Other Eukaryotes of Microbiological Interest: Parasitic Helminths and Vectors

Learning Outcomes

Arachnids

Learning Outcomes

Insects

Learning Outcomes

Chapter Summary

General Characteristics of Eukaryotic Organisms

Protozoa

Fungi

Algae

Water Molds

Other Eukaryotes of Microbiological Interest: Parasitic Helminths and Vectors

Questions for Review

Multiple Choice

Matching

Visualize It!

Short Answer

Fill in the Blanks

Critical Thinking

Concept Mapping

13 Characterizing and Classifying Viruses, Viroids, and Prions

Characteristics of Viruses

Learning Outcome

Genetic Material of Viruses

Learning Outcome

Hosts of Viruses

Learning Outcomes

Sizes of Viruses

Capsid Morphology

Learning Outcome

Viral Shapes

The Viral Envelope

Learning Outcome

Classification of Viruses

Learning Outcome

Viral Replication

Lytic Replication of Bacteriophages

Learning Outcome

Attachment 1

Entry 2

Synthesis 3

Assembly 4

Release 5

Lysogenic Replication of Bacteriophages

Learning Outcome

Replication of Animal Viruses

Learning Outcomes

Attachment of Animal Viruses

Entry and Uncoating of Animal Viruses

Synthesis of DNA Viruses of Animals

dsDNA Viruses

ssDNA Viruses

Synthesis of RNA Viruses of Animals

Positive-Sense ssRNA Viruses

Retroviruses

Negative-Sense ssRNA Viruses

dsRNA Viruses

Assembly and Release of Animal Viruses

Latency of Animal Viruses

The Role of Viruses in Cancer

Learning Outcomes

Culturing Viruses in the Laboratory

Learning Outcomes

Culturing Viruses in Mature Organisms

Learning Outcomes

Culturing Viruses in Bacteria

Culturing Viruses in Plants and Animals

Culturing Viruses in Embryonated Chicken Eggs

Culturing Viruses in Cell (Tissue) Culture

Learning Outcome

Are Viruses Alive?

Learning Outcome

Other Parasitic Particles: Viroids and Prions

Characteristics of Viroids

Learning Outcomes

Characteristics of Prions

Learning Outcomes

Chapter Summary

Characteristics of Viruses

Classification of Viruses

Viral Replication

The Role of Viruses in Cancer

Culturing Viruses in the Laboratory

Are Viruses Alive?

Other Parasitic Particles: Viroids and Prions

Questions for Review

Multiple Choice

Matching

Visualize It

Short Answer

Critical Thinking

Concept Mapping

14 Infection, Infectious Diseases, and Epidemiology

Symbiotic Relationships Between Microbes and Their Hosts

Types of Symbiosis

Learning Outcomes

Mutualism

Commensalism

Amensalism

Parasitism

Microbiome of Humans

Learning Outcome

Resident Microbiota

Transient Microbiota

Acquisition of the Microbiome

How Normal Microbiota Become Opportunistic Pathogens

Learning Outcome

Reservoirs of Infectious Diseases of Humans

Learning Outcome

Animal Reservoirs

Human Carriers

Nonliving Reservoirs

The Invasion and Establishment of Microbes in Hosts: Infection

Exposure to Microbes: Contamination and Infection

Learning Outcome

Portals of Entry

Learning Outcome

Skin

Mucous Membranes

Placenta

The Parenteral Route

The Role of Adhesion in Infection

Learning Outcomes

The Nature of Infectious Disease

Learning Outcome

Manifestations of Disease: Symptoms, Signs, and Syndromes

Learning Outcome

Causation of Disease: Etiology

Learning Outcomes

Using Koch’s Postulates

Exceptions to Koch’s Postulates

Virulence Factors of Infectious Agents

Learning Outcome

Extracellular Enzymes

Toxins

Exotoxins

Endotoxins

Antiphagocytic Factors

Capsules

Antiphagocytic Chemicals

The Stages of Infectious Diseases

Learning Outcome

Incubation Period

Prodromal Period

Illness

Decline

Convalescence

The Movement of Pathogens out of Hosts: Portals of Exit

Modes of Infectious Disease Transmission

Learning Outcomes

Contact Transmission

Vehicle Transmission

Vector Transmission

Classification of Infectious Diseases

Learning Outcomes

Epidemiology of Infectious Diseases

Learning Outcome

Frequency of Disease

Learning Outcomes

Epidemiological Studies

Learning Outcome

Descriptive Epidemiology

Analytical Epidemiology

Experimental Epidemiology

Hospital Epidemiology: Healthcare-Associated (Nosocomial) Infections

Learning Outcomes

Types of Healthcare-Associated Infections

Factors Influencing Healthcare-Associated Infections

Control of Healthcare-Associated Infections

Epidemiology and Public Health

Learning Outcome

The Sharing of Data Among Public Health Organizations

The Role of Public Health Agencies in Interrupting Disease Transmission

Public Health Education

Chapter Summary

Symbiotic Relationships Between Microbes and Their Hosts

Reservoirs of Infectious Diseases of Humans

The Invasion and Establishment of Microbes in Hosts: Infection

The Nature of Infectious Disease

The Movement of Pathogens Out of Hosts: Portals of Exit

Modes of Infectious Disease Transmission

Classification of Infectious Diseases

Epidemiology of Infectious Diseases

Questions for Review

Multiple Choice

Fill in the Blanks

Short Answer

Visualize It!

Critical Thinking

Concept Mapping

15 Innate Immunity

An Overview of the Body’s Defenses

Learning Outcomes

The Body’s First Line of Defense

The Role of Skin in Innate Immunity

Learning Outcome

The Role of Mucous Membranes in Innate Immunity

Learning Outcomes

The Role of the Lacrimal Apparatus in Innate Immunity

Learning Outcome

The Role of the Microbiome in Innate Immunity

Learning Outcome

Other First-Line Defenses

Learning Outcome

Antimicrobial Peptides

Other Processes and Chemicals

The Body’s Second Line of Defense

Learning Outcome

Defense Components of Blood

Learning Outcomes

Plasma

Defensive Blood Cells: Leukocytes

Lab Analysis of Leukocytes

Phagocytosis

Learning Outcome

Chemotaxis

Adhesion

Ingestion

Phagosome Maturation and Microbial Killing

Elimination

Nonphagocytic Killing

Learning Outcome

Killing by Eosinophils

Killing by Natural Killer Lymphocytes

Killing by Neutrophils

Nonspecific Chemical Defenses Against Pathogens

Learning Outcomes

Toll-like Receptors

NOD Proteins

Interferons

Type I (Alpha and Beta) Interferons

Type II (Gamma) Interferon

Complement

Complement Activation

Complement Cascade

Inflammation

Learning Outcome

Dilation and Increased Permeability of Blood Vessels

Migration of Phagocytes

Tissue Repair

Fever

Learning Outcome

Chapter Summary

An Overview of the Body’s Defenses

The Body’s First Line of Defense

The Body’s Second Line of Defense

Questions for Review

Multiple Choice

Modified True/False

Matching

Short Answer

Visualize It!

Critical Thinking

Concept Mapping

16 Adaptive Immunity

Overview of Adaptive Immunity

Learning Outcomes

Elements of Adaptive Immunity

The Tissues and Organs of the Lymphatic System

Learning Outcomes

The Lymphatic Vessels and the Flow of Lymph

Lymphoid Organs

Antigens

Learning Outcomes

Properties of Antigens

Types of Antigens

Preparation for an Adaptive Immune Response

Learning Outcomes

The Roles of the Major Histocompatibility Complex and Antigen-Presenting Cells

Antigen Processing

Processing Endogenous Antigens

Processing Exogenous Antigens

T Lymphocytes (T Cells)

Learning Outcomes

Specificity of the T Cell Receptor (TCR)

Types of T Lymphocytes

Cytotoxic T Lymphocyte

Helper T Lymphocyte

Regulatory T Lymphocyte

Clonal Deletion of T Cells

B Lymphocytes (B Cells) and Antibodies

Learning Outcomes

Specificity of a B Cell Receptor (BCR)

Diversity of B Cell Receptors

Specificity and Antibody Structure

Antibody Function

Activation of Complement and Inflammation

Neutralization

Opsonization

Agglutination

Antibody-Dependent Cell-Mediated Cytotoxicity (ADCC)

Classes of Antibodies

Clonal Deletion of B Cells

Immune Response Cytokines

Learning Outcome

Cell-Mediated Immune Resp

Delivery Info

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